Cancer is caused by the activity of rogue genes that act like street toughs within cells, forcing them to multiply out of control. Now, scientists say they've identified a kind of "kingpin" gene that rules this gang of delinquent DNA.Strange... but awesome! I wonder if the drug will come in Pikachu-shape chewibles for children.
"It's the 'leader of the pack,' and in that sense, it's a very effective target for therapy," said senior study author Dr. Pier Paolo Pandolfi, a pathologist at Memorial Sloan-Kettering Cancer Center in New York City.
Drugs to shut down the newly identified gene, which the researchers named POKEMON (for POK Erythroid Myeloid Ontogenic factor), could treat a wide spectrum of cancers, Pandolfi added, because other cancer-causing genes appear to lose their power when this key gene is switched off.
The findings are published in the Jan. 20 issue of Nature.
Tuesday, January 25, 2005
Key Cancer Gene Discovered
From Forbes.com:
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